If none of these solutions work, the file itself may be corrupt. Try copying the vector artwork into a file and re-assigning the stitch effects.
If the above steps fail, a complete, clean reinstall of the software is your best bet. This ensures that no corrupted files are left behind. wilcom e4 2 internal error 0x7101 occurred extra quality
Hold Ctrl + Shift while launching Wilcom → Click Yes to reset layout & display preferences. If none of these solutions work, the file