Old or missing drivers can cause false “missing exe” errors. Update via NVIDIA, AMD, or Intel’s official sites.
Resident Evil 5 supports both DirectX 9 and DirectX 10. re5dx9.exe launches the game in DirectX 9 mode, while re5dx10.exe launches it in DirectX 10 mode, which offers improved graphics and performance if your system and graphics card support it. re5dx9.exe download