Ayesha Kiran Mendes |verified| Access

Today, we are shining the spotlight on one such individual: .

Studying how proteins translocate to the outer mitochondrial membrane under stress. Neuropathy ayesha kiran mendes

[Normal Basal Conditions] HSPBs translocate into the Mitochondrial Intermembrane Space (IMS) -> Prevent Protein Aggregation [Heat Shock / Stress Conditions (42°C)] HSPBs immediately translocate to the Outer Mitochondrial Membrane (OMM) [P182L Mutant State (Pathological)] HSPBs enrich the OMM prematurely -> Triggers Mis-signaling -> Mitochondrial Dysfunction Today, we are shining the spotlight on one such individual: