Prison Break Is Sara Really Dead [work] -

Sarah Wayne Callies, the actress who played Sara, became pregnant before filming began on Season 3. Additionally, there were contractual disagreements between Callies and the network/producers regarding her role and shooting schedule.

Michael's reaction when he learns this? "They can change a face... but they can't change the DNA." (A line that directly contradicts the fact that Lincoln apparently saw the head close enough to identify it). prison break is sara really dead